| Title | CaO-P 2O
5 glass ceramics containing bioactive phases: crystallisation and in vitro bioactivity studies
|
| Publication Type | Journal Article |
| 2001 |
| Authors | Zhang, Y, Lopes, MA, Santos, JD |
| Journal | Key Engineering MaterialsKey Eng Mat |
| Volume | 192-195 |
| Issue | Uetikon-Zuerich, Switzerland |
| Pagination | 643 - 646 |
| Date Published | 2001/// |
| 10139826 (ISSN) |
| Bioactivity, Biomaterials, Ceramic materials, Crystal growth, Crystal microstructure, Crystalline materials, Crystalline phase, Crystallization, glass, Lime, Nucleating agents, Nucleation, Phosphates, Scanning electron microscopy, Simulated body fluid, X ray diffraction analysis, X ray photoelectron spectroscopy |
| CaO-P 2O
5 glass ceramics were prepared using a two-step heat treatment of nucleation and crystal growth using TiO
2 and Na
2O as nucleating agents. X-ray diffraction analysis demonstrated that bioactive and bioresorbable crystalline phases were precipitated in the microstructure, depending upon the relative content of the additives and of the CaO/P
2O
5 ratio of the glass. Ca
2P
2O
7 (β-DCP) was the main crystalline phase however β-Ca
3(PO
4)
2 (β-TCP), could also be formed by increasing the content of TiO
2 and the CaO/P
2O
5 ratio. Na and Ti-containing phases, CaTi
4(PO
4)
6, and/or NaTi
2(PO
4)
3, could also be assigned in the XRD spectra. In vitro testing in simulated body fluid (SBF) has proved the in vitro bioactivity of these glass ceramics with the formation of Ca-deficient apatite crystals, as demonstrated by Scanning Electron Microscopy (SEM) and X-ray photoelectron spectroscopy (XPS) analyses.
|
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