



@book {2384,
	title = {Microspheres based on hydroxyapatite nanoparticles aggregates for bone regeneration},
	series = {Key Engineering MaterialsKey Eng Mat},
	volume = {330-332 I},
	year = {2007},
	note = {Cited By (since 1996): 8Export Date: 21 November 2012Source: ScopusCODEN: KEMAELanguage of Original Document: EnglishCorrespondence Address: Pataquiva Mateus, A.Y.; INEB - Institute de Engenharia Biom{\'e}dica, Laborat{\'o}rio de Biomateriais, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal; email: yovana@ibmc.up.ptReferences: Liou, S., Chen, S., Liu, D., (2003) Biomaterials, 24, p. 3981;Gauthier, O., Bouler, J., Weiss, P., Bosco, J., Daculsi, G., Aguado, E., (1999) Journal of Biomedical Materials Research, 47, p. 28; 
Grimaldi, G., Weiss, P., Millot, F., Daculsi, G., (1998) Journal of Biomedical Materials Research, 39, p. 660; 
Termenoff, J., Mikos, A., (2000) Biomaterials, 21, p. 2405; 
Best, S., Bonfield, W., Doyle, C., (1989) Bioceramics, p. 68. , Oonishi H, Aoki H, Sawai K, editors, Tokyo: Ishiyaku Euro-America; 
Pataquiva-Mateus, A.Y., Ferraz, M.P., Monteiro, F.J., Journal of Biomedical Materials Research, , Submitted paper
},
	month = {2007///},
	pages = {243 - 246},
	abstract = {This study concerns the preparation and characterisation of microspheres associating alginate and two different types of hydroxyapatite (HA), which are intended to be used as drug delivery systems and bone regeneration matrices. Hydroxyapatite nanoparticles (HA-1 and HA-2) were prepared using a chemical precipitation synthesis based on H3PO4, Ca(OH)2 and a surfactant, SDS (sodium dodecylsulphate), as starting reagents. These two powders of nanoHA and alginate were used to prepare two different types of microspheres. Both powders and microspheres were characterised using FTIR, TEM, SEM, mercury porosimetry analysis and X-ray diffraction Results show that pure hydroxyapatite (HA) and mixtures of HA/β-TCP in the nanometre range were obtained from both HA syntheses. Microspheres with different characteristics were obtained from these two types of hydroxyapatite.},
	keywords = {Alginate, Bone, Bone Regeneration, Chemical precipitation, Controlled drug delivery, Fourier transform infrared spectroscopy, hydroxyapatite, Microspheres, Microstructure, nanoparticles, Nanostructured materials, Scanning electron microscopy, Surface active agents, transmission electron microscopy},
	isbn = {10139826 (ISSN)},
	url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-33846333853\&partnerID=40\&md5=f694c3d331dea2c82aba11cef4dddd59},
	author = {Pataquiva Mateus, A.Y. and Ferraz, M.P. and Monteiro, F.J.}
}
