



@article {2529,
	title = {A novel urethane containing copolymer as a surface modification additive for blood contact materials},
	journal = {Journal of Materials Science: Materials in MedicineJ. Mater. Sci. Mater. Med.},
	volume = {13},
	year = {2002},
	note = {Cited By (since 1996): 6Export Date: 21 November 2012Source: ScopusCODEN: JSMMEdoi: 10.1023/A:1015789726455Language of Original Document: EnglishCorrespondence Address: Ji, J.; Department of Polymer Science, Zhejiang University, HangZhou 310027, China; email: jianji@mail.hz.zj.cnReferences: Elbert, D., Hubbell, J., (1996) Annu. Rev. Mater., p. 365;Munro, M., Quattrone, A., Ellsworth, S., Kulkarni, P., Eberhart, R., (1981) Trans. Am. Soc. Artif. Intern. Organs., p. 499; 
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},
	month = {2002///},
	pages = {677 - 684},
	abstract = {Surface modification to develop a biomolecules-presenting surface is of interest, both from a scientific and an industrial point of view. In this research, a penta-block-coupling polymer of warfarin-PEO-MDI-PEO-warfarin was specially designed as the surface modifying additive (SMA). The warfarin-modified polyurethane surfaces were then prepared by dip-coating method. Attenuated total reflection fourier transform infra-red (ATR-FTIR) spectra revealed that the urethane segments in the SMA could penetrate into the hard block of segmented polyurethane (SPU) via intermolecular hydrogen bonds. The X-ray photoelectron spectroscopy (XPS) results indicated that the intermolecular hydrogen bonds were strong enough to form stable warfarin-PEO composite surfaces in an aqueous environment. Fibrinogen and albumin adsorption onto unmodified and SMA-modified SPU was investigated by the                        125l-labeled method. The surface for attracting and reversibly binding albumin, which was proved to suppress the platelet adhesion and prolong the clotting time, has been developed by the simple coating of the novel SMA in SPU. {\textcopyright} 2002 Kluwer Academic Publishers.
},
	keywords = {Adhesion, Adsorption, Albumin, article, Attenuation, biomaterial, Block copolymers, Blood, blood clotting time, Chemical modification, Coatings, copolymer, fibrinogen, Fourier transform infrared spectroscopy, human, human cell, hydrogen bond, Hydrogen bonds, infrared spectroscopy, iodine 125, material coating, Polyurethanes, priority journal, Surface modifying additives (SMA), surface property, Surface treatment, synthesis, thrombocyte adhesion, urethan, warfarin, X ray photoelectron spectroscopy},
	isbn = {09574530 (ISSN)},
	url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-0036308146\&partnerID=40\&md5=4767c8a335b26ea0390bc42ddbbaf6b1},
	author = {Ji, J. and Barbosa, M.A. and Feng, L. and Shen, J.}
}
