



@article {2538,
	title = {Stearyl poly(ethylene oxide) grafted surfaces for preferential adsorption of albumin},
	journal = {BiomaterialsBiomaterials},
	volume = {22},
	year = {2001},
	note = {Cited By (since 1996): 26Export Date: 21 November 2012Source: ScopusCODEN: BIMADdoi: 10.1016/S0142-9612(01)00048-5PubMed ID: 11575476Language of Original Document: EnglishCorrespondence Address: Ji, J.; Department of Polymer Science, Zhejiang University, Hangzhou 310027, China; email: @@@Chemicals/CAS: Biocompatible Materials; Fibrinogen, 9001-32-5; Ligands; polyethylene glycol-polystyrene; Polyethylene Glycols; Polystyrenes; Serum Albumin; Stearates; stearyl poly(ethylene oxide)References: Andrade, J.D., Nagaoka, S., Cooper, S., Okano, T., Kim, S.W., Surface and blood compatibility; current hypothesis (1987) ASAIO Trans, 33 (2), pp. 75-76;Ranter, B.D., The engineering of biomaterials exhibiting recognition and specificity (1996) J Mol Recognition, 9, pp. 617-625; 
Jeon, S.I., Lee, J.H., Andrade, J.D., De Gennes, P.G., Protein-surface interactions in the presence of polyethylene oxide (1991) J Colloid Interface Sci, 142 (1), pp. 149-158; 
Merrill, E.W., Salzman, E.W., Polyethylene oxide as a biomaterial (1983) ASAIO J, 6, pp. 60-64; 
Amiji, M., Park, K., Prevention of protein adsorption and platelet adhesion on surfaces by PEO/PPO/PEO triblock copolymers (1992) Biomaterials, 13, pp. 682-692; 
Mayes, A.M., Irine, D.J., Tailoring polymer surface for control cell behavior (1998), pp. 73-84. , Thomson G., Mooney R.C., Healy D.J., Ikada K.E., Mikos Y. (Eds.), Biomaterials regulating cell function and tissue development, Warrendale, PA: MRSKeogh, R.J., Eaton, J.W., Albumin binding surfaces for biomaterials (1994) J Lab Clin Med, 124 (4), pp. 537-545; 
Munro, M.S., Quattrone, A.J., Ellsworth, S.R., Kulkarni, P., Eberhart, R.C., Alkyl substituted polymers with enhanced albumin affinity (1981) Trans Am Soc Artif Intern Organs, 27, pp. 499-503; 
Pitt, W.G., Cooper, S.L., Albumin adsorption on alkyl chain derivatized polyurethane; I. The effect of C-18 alkylation (1988) J Biomed Mater Res, 22, pp. 359-382; 
Frautschi, J.R., Munro, M.S., Lloyd, D.R., Eberhart, R.C., Alkyl derivatized cellulose acetate membranes with enhanced albumin affinity (1983) Trans Am Soc Artif Intern Organs, 29, pp. 242-244; 
Keogh, J.R., Velander, F.F., Eaton, J.W., Albumin-binding surface for implantable devices (1992) J Biomed Mater Res, 26, pp. 441-456; 
Qiu, Y.X., Yu, X.J., Feng, L.X., Yang, S.L., Synthesis and characterization of amphiphilic and microphase-separated graft copolymer (1992) Makromol Chem, 173, p. 1377; 
Gallo BM, Russo S. In: Platzer NAJ, editor. Copolymer, polymers and composites. Washington, DC, 1975. p. 85Neumann AW, Good RJ. In: Good RJ, Stromberg RR, editors. Surface and colloid science, vol. 11, Experimental methods. New York: Plenum Press, 1979. p. 31Brash, J.L., Davidson, V.J., Adsorption of glass and polyethylene from solutions of fibrinogen and albumin (1976) Thromb Res, 9 (3), pp. 249-259; 
Lide DR. In: Lider DR, editor. Surface tension of common liquids, Handbook of chemistry and physics. Boca Raton, FL: CRC Press, 1996. p. 6-147Carel, J.V.O., (1994), pp. 170-177. , Carel J.V.O. (Ed.), Interfacial forces in aqueous media, New York: Marcel DekkerMori, Y., Nagaoka, S., Takiuchi, H., Kikuci, T., Noguchi, N., Tanzawa, H., Noishili, Y., A new antithrombogenic material with long polyethyleneoxide chains (1982) Trans Am Soc Artif Intern Organs, 28, pp. 459-463; 
Wu, D., Jian, K., (1995) Sci China (B), 25 (11), p. 1121; 
Wu, D., Jian, K., (1995) Sci China (B), 26 (5), p. 409; 
Walton, D.G., Soo, P.P., Mayes, A.M., Sofia Allgor, S.J., Fujii, J.T., Griffith, L.G., Ankner, J.F., Satija, S.K., Creation of stable poly(ethylene oxide) surfaces on poly(methyl methacrylate) using blends of branched and linear polymer (1997) Macromolecules, 30 (22), pp. 6947-6956; 
Walton, D.G., Mayes, A.M., Entropically driven segregation in blend of branched and liner polymers (1996) Phys Rev E, 54 (3), pp. 2811-2815
},
	month = {2001///},
	pages = {3015 - 3023},
	abstract = {An ideal surface for many biomedical applications would resist non-specific protein adsorption while at the same time triggering a specific biological pathway. Based on the approach of selectively binding albumin to free fatty acids, stearyl groups were immobilized onto poly(styrene) backbone via poly(ethylene oxide) side chains. X-ray photoelectron spectroscopy (XPS) analysis indicates substantial surface enrichment of the stearyl poly(ethylene oxide) (SPEO). In an aqueous environment, the surface rearrangement is limited, as proved by dynamic contact angle tests. The comb-like copolymer presents a special hydrophobic surface with high SPEO surface density, which may be due to the {\textquoteright}tail like{\textquoteright} SPEO architecture at the copolymer/water interface. Protein adsorption tests confirm that the comb-like surfaces adsorb high levels of albumin and resist fibrinogen adsorption very significantly. The surfaces prepared in this research attract and reversibly bind albumin due to the synergistic action of the PEO chains and the stearyl end groups. Copyright {\textcopyright} 2001 Elsevier Science Ltd.},
	keywords = {Adsorption, Albumin, Amphiphilic copolymer, article, Biocompatible Materials, Biomedical engineering, Catalyst selectivity, Cell immobilization, Contact angle, copolymer, Copolymers, density, Electron Probe Microanalysis, fibrinogen, Grafting (chemical), Humans, hydrophobicity, Ligands, macrogol, macrogol derivative, materials testing, Polyethylene Glycols, Polystyrenes, priority journal, Protein adsorption, protein binding, Proteins, roentgen spectroscopy, Serum Albumin, Stearates, Stearyl end groups, Surface Properties, surface property, Ultraviolet spectroscopy, X ray photoelectron spectroscopy},
	isbn = {01429612 (ISSN)},
	url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-0035889824\&partnerID=40\&md5=9e163aafab1e37712839a8c35e902110},
	author = {Ji, J. and Feng, L. and Barbosa, M.A.}
}
