



@book {2437,
	title = {In vitro biodegradability of chitosan-organosiloxane hybrid membrane},
	series = {Key Engineering MaterialsKey Eng Mat},
	volume = {284-286},
	year = {2005},
	note = {Cited By (since 1996): 2Export Date: 21 November 2012Source: ScopusCODEN: KEMAELanguage of Original Document: EnglishCorrespondence Address: Tsuru, K.; Faculty of Engineering, Biomaterial Laboratory, Okayama University, Tsushima, Okayama 700-8530, Japan; email: kanji@cc.okayama-u.ac.jpReferences: Chandy, T., Sharma, P.C., (1990) Biomat Art Cells Art Org, 18, pp. 1-24;Ren, L., Tsuru, K., Hayakawa, S., Osaka, A., (2001) J Ceram Soc Japan, 109, pp. 403-408; 
Ren, L., Tsuru, K., Hayakawa, S., Osaka, A., (2002) Biomaterials, 23, pp. 4765-4773; 
Shirosaki, Y., Tsuru, K., Hayakawa, S., Osaka, A., Lopes, M.A., Santos, J.D., Fernandes, M.H., (2004) Key Engineering Materials, 254-256, pp. 857-860; 
Shirosaki, Y., Tsuru, K., Hayakawa, S., Osaka, A., Lopes, M.A., Santos, J.D., Fernandes, M.H., (2005) Biomaterials, 26, pp. 485-493; 
S. Prochazkova, K. M. V{\r a}rum, K. {\O}stgaard, Carbohydrate Polymers, 38 (1999), p. 115-122Brinker, J.C., Scherer, G.W., (1989) Sol-Gel Science, The Physics and Chemistry of Sol-Gel Processing, , Academic Press, San Diego
},
	month = {2005///},
	pages = {823 - 826},
	abstract = {Chitosan-silicate hybrid membranes were prepared using γ- glycidoxypropyltrimethoxysilane (GPSM) through a sol-gel process. The amino groups of chitosan chains were reacted with the epoxy groups of GPSM and GPSM have a function as the agent to cross-link the chitosan chains. The cross-linking degree of the hybrid membranes was determined by ninhydrin assay. Fourier-transform infrared (FT-IR) spectroscopy and                        29Si cross-polarization (CP) magic-angle spinning (MAS)-NMR spectroscopy were used to assess the structure of the hybrid membranes. The biodegradability of the hybrid membranes in phosphate-buffered saline solution or lysozyme solution was investigated as a function of the GPSM concentration.
},
	keywords = {biodegradability, Biological membranes, chitosan, Chitosan chains, Chitosan inorganic hybrid membranes, Chitosan-lnorganlc hybrid, Crosslinking, Fourier transform infrared spectroscopy, Nuclear magnetic resonance spectroscopy, R- glycidoxypropyltrimethoxysilane GPSM, Reaction kinetics, Silicates, Sol-gel process},
	isbn = {10139826 (ISSN)},
	url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-34249091650\&partnerID=40\&md5=51e1b69bd7dc1b4c23b022e4ec338e8a},
	author = {Tsuru, K. and Shirosaki, Y. and Hayakawa, S. and Osaka, A. and Lopes, M.A. and Santos, J.D. and Fernandas, M.H.}
}
@book {2488,
	title = {Biological Activity of Two Glass Ceramics in the Meta- and Pyrophosphate Region: A Comparative Study},
	series = {Key Engineering MaterialsKey Eng Mat},
	volume = {254-256},
	year = {2004},
	note = {Conference code: 62053Cited By (since 1996): 2Export Date: 21 November 2012Source: ScopusCODEN: KEMAELanguage of Original Document: EnglishCorrespondence Address: Dias, A.G.; Faculdade de Engenharia, Universidade do Porto, DEMM, Rua Dr. Roberta Frias, 4200 Porto, PortugalReferences: Dias, A.G., Lopes, M.A., Gibson, I., Santos, J.D., J. Non-Crystal. Solids, , in press;Dias, A.G., Lopes, M.A., Tsuru, K., Hayakawa, S., Santos, J.D., Osaka, A., Physiscs and Chemistry of Glasses, , in press; 
Dias, A.G., Lopes, M.A., Santos, J.D., Advance Materials Science, , in press; 
Rykke, M., Rolla, G., Sonju, T., (1988) Scand. J. Dent. Res., 96, pp. 517-522
},
	month = {2004///},
	pages = {825 - 828},
	address = {Porto},
	abstract = {Based upon the CaO-P                        2O
                        5 glass system, two glass ceramics were prepared in the metaand pyrophosphate regions. The present work describes preliminary results concerning the biological activity of MK5B (45CaO-45P
                        2O
                        5-5MgO-5K20, in mol \%) and MT13B (45CaO-37P
                        2O
                        55-5MgO-13TiO
                        2, in mol \%) using MG63 osteoblast-like cells. Both materials supported cell growth and proliferation which increased with the incubation time. However, cell growth was significantly lower on seeded MK5B samples. SEM observation showed that cell adhesion and spreading were hampered on this material. Evident degradation of the material surface was observed with simultaneous cell proliferation and material precipitation. By contrast, MT13B presented a relatively stable surface throughout the culture time. Results suggest that the in vitro biological behaviour of MK5B and MT13B is related with differences in the degradation rates of the two materials during the culture time.
},
	keywords = {Adhesion, Biodegradable glass ceramics, Biodegradation, Bone, cell proliferation, Cells, Crystallization, Degradation, Glass ceramics, incubation time, MG63 osteoblast-like cells, Scanning electron microscopy, X ray diffraction},
	isbn = {10139826 (ISSN)},
	url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-0348146001\&partnerID=40\&md5=5245524d4dfb5615946aadcf5eb7c37a},
	author = {Dias, A.G. and Costa, M.A. and Lopes, M.A. and Santos, J.D. and Fernandas, M.H.},
	editor = {Barbosa M.A. and Monteiro F.J. and Correia R. and Leon B.}
}
