



@article {3317,
	title = {Study of the isoflavone content of different extracts of Medicago spp. as potential active ingredient},
	journal = {Industrial Crops and Products},
	volume = {57},
	year = {2014},
	note = {Export Date: 21 November 2014},
	month = {2014},
	pages = {110 - 115},
	abstract = {This study focuses on the isoflavones composition of different extracts of Medicago species (M. minima, M. tornata, M. truncatula, M. rigidula, M. scutelata, M. segitalis and M. sativa), a leguminous crop used as animal feeding. There are some research studies on the isoflavones composition of Medicago sativa, but no comprehensive profile of isoflavones has been reported for these other six species. In this work, two glycosides (daidzin and genistin) and six aglycones (daidzein, glycitein, genistein, formononetin, prunetin and biochanin A) were determined by high performance liquid chromatography (HPLC/DAD) in three different extracts of these species: aqueous, hydroalcoholic and alcoholic. In all samples genistin, daidzein and genistein were the most abundant isoflavone compounds. The highest concentration of genistin was observed in the extracts of M. scutelata (5.2 and 9.6. mg/kg. db, respectively, for hydroalcoholic and alcoholic extract), in amounts 2-4.5-fold higher than the other samples evaluated. Daidzein is also present in high amounts in M. scutelata (19.2. mg/kg. db, alcoholic extract). Genistein is detected in several species at concentrations ranging from 0.7 (aqueous extract of M. tornata) to 16.1. mg/kg. db (alcoholic extract of M. scutelata). In terms of total isoflavones content per species, results showed significant differences between M. rigidula and M. sativa, considering all type of solvents, being the highest and the lowest one, respectively. In a general way, the extractability of compounds significantly increased from aqueous to alcoholic extracts. The study demonstrates that some Medicago species possess an excellent potential as a source of these health promoting bioactive compounds. {\textcopyright} 2014 Elsevier B.V.},
	keywords = {By-product, Daidzein, Genistein, Genistin, Isoflavones, Medicago},
	url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84898621595\&partnerID=40\&md5=a2c78b9a016fd634ffb0ef4dbedcde5f},
	author = {Rodrigues, F. and Almeida, I. and Sarmento, B. and Amaral, M.H. and Oliveira, M.B.P.P.}
}
@article {3309,
	title = {What do Portuguese women prefer regarding vaginal products? Results from a cross-sectional web-based survey},
	journal = {Pharmaceutics},
	volume = {6},
	year = {2014},
	note = {Export Date: 21 November 2014},
	month = {2014},
	pages = {543 - 556},
	abstract = {Therapeutic outcomes of vaginal products depend not only on their ability to deliver drugs to or through the vagina but also on acceptability and correct use. Women{\textquoteright}s preferences, in turn, may vary according to age and cultural backgrounds. In this work, an anonymous online survey was completed by 2529 Portuguese women to assess their preferences for physical characteristics and mode of application of vaginal products, according to age. Additionally, intention to use and misconceptions about these issues were assessed. The majority of women of all age groups would use vaginal products to treat or prevent diseases, upon medical prescription. Women preferred vaginal products to be odorless and colorless gels, creams and ointments composed by natural origin drugs/excipients and applied by means of an applicator. Although the majority of women would prefer not to insert any product in the vagina, intention to use for self and recommendation to use for others was associated with previous experiences with vaginal products. General concerns and misconceptions related to use of vaginal products were rare. These data may contribute to the development of products that women are more prone to use.},
	keywords = {Acceptability, Vaginal dosage forms, Vaginal products, Women{\textquoteright}s preferences},
	url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84908210757\&partnerID=40\&md5=5515e40e97ff157b0a5b4498557008ef},
	author = {Palmeira-de-Oliveira, R. and Duarte, P. and Palmeira-de-Oliveira, A. and Das Neves, J. and Amaral, M.H. and Breitenfeld, L. and Martinez-de-Oliveira, J.}
}
@article {2853,
	title = {Medicago spp. extracts as promising ingredients for skin care products},
	journal = {Industrial Crops and Products},
	volume = {49},
	year = {2013},
	note = {Export Date: 12 December 2013Source: Scopus},
	month = {2013///},
	pages = {634 - 644},
	url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84880378375\&partnerID=40\&md5=1b60aaf1efb444f653b44800529f5ae3},
	author = {Rodrigues, F. and Palmeira-de-Oliveira, A. and Das Neves, J. and Sarmento, B. and Amaral, M.H. and Oliveira, M.B.}
}
