



@article {2523,
	title = {Silicon and iron levels in tissues of animals treated with a "ferrimagnetic ceramic" with oncotherapeutic potential (anti-tumor) value},
	journal = {Journal of Trace Elements in Medicine and BiologyJ. Trace Elem. Med. Biol.},
	volume = {16},
	year = {2002},
	note = {Cited By (since 1996): 2Export Date: 21 November 2012Source: ScopusCODEN: JTEBFdoi: 10.1016/S0946-672X(02)80054-2PubMed ID: 12530589Language of Original Document: EnglishCorrespondence Address: Bastos, M.D.L.; Toxicology Department, Faculty of Pharmacy, University of Porto, Rua An{\'\i}bal Cunha 164, 4050 Porto, PortugalChemicals/CAS: calcium oxide, 1305-78-8; iron, 14093-02-8, 53858-86-9, 7439-89-6; phosphorus pentoxide, 1314-56-3; silicon dioxide, 10279-57-9, 14464-46-1, 14808-60-7, 15468-32-3, 60676-86-0, 7631-86-9; silicon, 7440-21-3; Biocompatible Materials; Ceramics; Iron, 7439-89-6; Silicon, 7440-21-3; Tissue ExtractsReferences: Rofstad, E.K., Brustad, T., Primary and secondary cell death in human melanoma xenografts following hyperthermic treatment (1986) Cancer Res., 46, pp. 355-361;Nishimura, Y., Shibamoto, Y., Jo, S., Akuta, K., Hiraoka, M., Takahashi, M., Abe, M., Relationship between heat-induced vascular damage and thermosensitivity in four mouse tumors (1988) Cancer Res., 48, pp. 7226-7230; 
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},
	month = {2002///},
	pages = {255 - 259},
	abstract = {The stability in a biological environment of an injectable cement with oncotherapeutic potential - consisting of a glass powder of SiO                        2 (35.6\%), CaO (42.4\%), P
                        2O
                        5 (17\%), Na
                        2O (5\%) and 30\% of its weight of Fe
                        3O
                        4 dissolved in (NH
                        4)
                        2HPO
                        4 plus NH
                        4H
                        2PO
                        4 - was evaluated referring to the release of silicon and iron. The experimental model was the rat, and organs (liver, kidney, spleen, lung, heart, and brain) of the implanted and control animals were collected for quantification of these elements by electrothermal atomization atomic absorption spectrometry methods. In most of the analysed organs no significant difference in the contents of silicon and iron between the implanted and the control animals was found.
},
	keywords = {animal model, animal tissue, Animalia, Animals, article, atomic absorption spectrometry, Biocompatible Materials, calcium oxide, cancer therapy, cement, ceramics, controlled study, experimental model, Ferrimagnetic ceramic, heat, Humans, implant, Iron, Magnetics, materials testing, Neoplasms, nonhuman, Oncotherapy, phosphorus pentoxide, powder, priority journal, Prostheses and Implants, rat, Rats, Reproducibility of Results, Silicon, silicon dioxide, tissue distribution, Tissue Extracts},
	isbn = {0946672X (ISSN)},
	url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-12244289604\&partnerID=40\&md5=aab427a78a1678c3b3f96bf869160dfd},
	author = {Almeida, T. and Soares, M.E. and Cavalheiro, J. and Bastos, M.D.L.}
}
