| Title | Microstructural characterization and in vitro apatite formation in CaO-P 2O
5-TiO
2-MgO-Na
2O glass-ceramics
|
| Publication Type | Journal Article |
| 2001 |
| Authors | Zhang, Y, Santos, JD |
| Journal | Journal of the European Ceramic SocietyJ Eur Ceram Soc |
| Volume | 21 |
| Issue | 2Exeter, United Kingdom |
| Pagination | 169 - 175 |
| Date Published | 2001/// |
| 09552219 (ISSN) |
| Apatite, Bioactivity, Calcium phosphate glass, Ceramic materials, Crystal microstructure, Crystallization, dissociation, glass, Glass ceramics, Leaching, Lime, Magnesia, Phosphorus Compounds, Porous materials, Sodium compounds, Solubility, Titanium dioxide |
| Bulk calcium phosphate glass and glass-ceramic with CaO/P 2O
5 molar ratio = 1.25 were prepared through introducing small amounts of Na
2O, MgO, and TiO
2 into the glass. Using XRD analysis, biocompatible β-Ca
2P
2O
7 (β-DCP) and more soluble Ca and Na-containing phases were clearly identified in the microstructure. In vitro bioactivity was assessed by immersion testing in SBF-simulated body fluid and apatite crystals were formed after 4 and 8 weeks of soaking. Porous microstructure was produced through dissolution of soluble phases and desirable porous structure may be achieved by controlling size and distribution of these phases and the leaching process. Therefore, this glass-ceramic is expected to be used as bone repair and regeneration implants and drug delivery carrier.
|
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