| Title | Mineralization of regenerated cellulose hydrogels induced by human bone marrow stromal cells |
| Publication Type | Journal Article |
| 2005 |
| Authors | Granja, PL, De Jéso, B, Bareille, R, Rouais, F, Baquey, C, Barbosa, MA |
| Journal | European Cells and MaterialsEur. Cells and Mater. |
| Volume | 10 |
| Pagination | 31 - 39 |
| Date Published | 2005/// |
| 14732262 (ISSN) |
| article, bone marrow cell, Bone Marrow Cells, bone mineralization, Calcification, Physiologic, Calcium phosphates, Cell culture, cell proliferation, cell regeneration, Cells, Cultured, Cellulose, hematopoietic stem cell, human, Human bone marrow stromal cells, human cell, Humans, hydrogel, Hydrogels, hydroxyapatite, in vitro study, mineralization, Regenerated cellulose hydrogels, Regeneration, Spectroscopy, Fourier Transform Infrared, stroma cell, Stromal Cells, Time series analysis |
| The proliferation of cultured human bone marrow stromal cells (HBMSC) on regenerated cellulose hydrogels was assessed. Regenerated cellulose hydrogels showed good rates of HBMSC proliferation, the cells exhibiting a flattened morphology, and after 22 days in culture, the cells had homogeneously colonized the surface of the materials. Moreover, since the early days in culture, between the surface of the materials and attached cells a continuous granulated hydroxyapatite layer was formed. It has been previously demonstrated in vitro, but without cells, that these materials did not mineralize. Hence, it seems that HBMSC promoted the mineralization of the surface. |
| http://www.scopus.com/inward/record.url?eid=2-s2.0-28444434484&partnerID=40&md5=336e1872af4f9b4274cda0b46e091486 |
