| Title | Physical characterization of hydroxyapatite porous scaffolds for tissue engineering |
| Publication Type | Journal Article |
| 2009 |
| Authors | Teixeira, S, Rodriguez, MA, Pena, P, De Aza, AH, De Aza, S, Ferraz, MP, Monteiro, FJ |
| Journal | Materials Science and Engineering CMater. Sci. Eng. C |
| Volume | 29 |
| Issue | 5 |
| Pagination | 1510 - 1514 |
| Date Published | 2009/// |
| 09284931 (ISSN) |
| Apatite, Bone, Bone regenerations, Bone tissue engineerings, Ceramic materials, Ceramic slurries, Fourier-transformed infrared spectroscopies, hydroxyapatite, infrared spectroscopy, Macro-pores, Mechanical testing, Physical characterizations, Polymer blends, Polymer replications, Polymers, Polyurethane sponges, Pore interconnectivity, Porous hydroxyapatites, Porous scaffolds, Scaffolds, Scanning electron microscopy, Spectroscopic analysis, Starting materials, Thermal cycles, Tissue engineering, X- ray diffractions |
| The present study refers to the preparation and characterization of porous hydroxyapatite scaffolds to be used as matrices for bone regeneration or as specific release vehicles. Ceramics are widely used for bone tissue engineering purposes and in this study, hydroxyapatite porous scaffolds were produced using the polymer replication method. Polyurethane sponges were used as templates and impregnated with a ceramic slurry at different ratios, and sintered at 1300 °C following a specific thermal cycle. The characteristics of the hydroxyapatite porous scaffolds and respective powder used as starting material, were investigated by using scanning electron microscopy, particle size distribution, X-ray diffraction, Fourier transformed infrared spectroscopy and compressive mechanical testing techniques. It was possible to produce highly porous hydroxyapatite scaffolds presenting micro and macropores and pore interconnectivity. © 2008 Elsevier B.V. All rights reserved. |
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