| Title | Porous HA scaffolds for drug releasing |
| Publication Type | Book |
| Year of Publication | 2005 |
| Authors | Queiroz, AC, Santos, JD, Monteiro, FJ |
| Series Title | Key Engineering MaterialsKey Eng Mat |
| Volume | 284-286 |
| Number of Pages | 407 - 410 |
| ISBN Number | 10139826 (ISSN) |
| Keywords | Adsorption, ampicillin, Controlled drug delivery, Drug release, hydroxyapatite, orthopedics, Porous hydroxyapatite, Porous hydroxyapatites, Porous materials, Scaffolds, Sodium ampicillin, Surgery, Surgery rooms |
| Abstract | Dense and porous hydroxyapatite materials aimed at being used in controlled drug delivery, were characterised and studied in order to evaluate their ability to adsorb and release sodium ampicillin in a controlled manner, as a model for a drug delivery system, potentially applicable associated to surgery for the treatment of bone defects. These porous materials should also have adequate mechanical strength to withstand manipulation and sculpturing in surgery room. Adsorption and release profiles were obtained for a range of porous materials, leading to higher adsorption rates and more adequate release profiles than for dense materials. |
| URL | http://www.scopus.com/inward/record.url?eid=2-s2.0-34248995543&partnerID=40&md5=db9f063f6d3b98c88a9d87c693ada572 |
