Title | Silicon and iron levels in tissues of animals treated with a "ferrimagnetic ceramic" with oncotherapeutic potential (anti-tumor) value |
Publication Type | Journal Article |
| 2002 |
Authors | Almeida, T, Soares, ME, Cavalheiro, J, Bastos, MDL |
Journal | Journal of Trace Elements in Medicine and BiologyJ. Trace Elem. Med. Biol. |
Volume | 16 |
Issue | 4 |
Pagination | 255 - 259 |
Date Published | 2002/// |
| 0946672X (ISSN) |
| animal model, animal tissue, Animalia, Animals, article, atomic absorption spectrometry, Biocompatible Materials, calcium oxide, cancer therapy, cement, ceramics, controlled study, experimental model, Ferrimagnetic ceramic, heat, Humans, implant, Iron, Magnetics, materials testing, Neoplasms, nonhuman, Oncotherapy, phosphorus pentoxide, powder, priority journal, Prostheses and Implants, rat, Rats, Reproducibility of Results, Silicon, silicon dioxide, tissue distribution, Tissue Extracts |
| The stability in a biological environment of an injectable cement with oncotherapeutic potential - consisting of a glass powder of SiO 2 (35.6%), CaO (42.4%), P
2O
5 (17%), Na
2O (5%) and 30% of its weight of Fe
3O
4 dissolved in (NH
4)
2HPO
4 plus NH
4H
2PO
4 - was evaluated referring to the release of silicon and iron. The experimental model was the rat, and organs (liver, kidney, spleen, lung, heart, and brain) of the implanted and control animals were collected for quantification of these elements by electrothermal atomization atomic absorption spectrometry methods. In most of the analysed organs no significant difference in the contents of silicon and iron between the implanted and the control animals was found.
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