| Title | In vitro biodegradability of chitosan-organosiloxane hybrid membrane |
| Publication Type | Book |
| Year of Publication | 2005 |
| Authors | Tsuru, K, Shirosaki, Y, Hayakawa, S, Osaka, A, Lopes, MA, Santos, JD, Fernandas, MH |
| Series Title | Key Engineering MaterialsKey Eng Mat |
| Volume | 284-286 |
| Number of Pages | 823 - 826 |
| ISBN Number | 10139826 (ISSN) |
| Keywords | biodegradability, Biological membranes, chitosan, Chitosan chains, Chitosan inorganic hybrid membranes, Chitosan-lnorganlc hybrid, Crosslinking, Fourier transform infrared spectroscopy, Nuclear magnetic resonance spectroscopy, R- glycidoxypropyltrimethoxysilane GPSM, Reaction kinetics, Silicates, Sol-gel process |
| Abstract | Chitosan-silicate hybrid membranes were prepared using γ- glycidoxypropyltrimethoxysilane (GPSM) through a sol-gel process. The amino groups of chitosan chains were reacted with the epoxy groups of GPSM and GPSM have a function as the agent to cross-link the chitosan chains. The cross-linking degree of the hybrid membranes was determined by ninhydrin assay. Fourier-transform infrared (FT-IR) spectroscopy and 29Si cross-polarization (CP) magic-angle spinning (MAS)-NMR spectroscopy were used to assess the structure of the hybrid membranes. The biodegradability of the hybrid membranes in phosphate-buffered saline solution or lysozyme solution was investigated as a function of the GPSM concentration.
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| URL | http://www.scopus.com/inward/record.url?eid=2-s2.0-34249091650&partnerID=40&md5=51e1b69bd7dc1b4c23b022e4ec338e8a |
