INEB researchers are the editors of the book: "Mucosal Delivery of Biopharmaceuticals"
INEB researchers, José das Neves and Bruno Sarmento, are the editors of the book: "Mucosal Delivery of Biopharmaceuticals: Biology, Challenges and Strategies". This book was published by Springer.
The book provides a concise and up-to-date overview of the biological features justifying the use of different human mucosa as delivery routes for biopharmaceuticals as well as the technological strategies that have been followed so far regarding the optimization of mucosal potentialities.
The book also addresses the challenges that arise with the advent of new biopharmaceutical drugs and alternative means of administration. After a brief introduction, the first section addresses general aspects of the biology of mucosal tissues and their unique aspects towards beneficial or deleterious interactions with biopharmaceuticals and delivery systems.
The second part is dedicated to the different delivery strategies that have recently been investigated for different mucosal sites.
The third section describes the development and clinical applications, either factual or potential, of particular pharmaceutical delivery systems and products enclosing biopharmaceuticals for mucosal delivery.
Special focus is set on the most successful case studies of recent years by field experts or those engaged in developing such solutions in a concise and practical way. The last section briefly centers on pertinent aspects about the regulatory, toxicological and market issues of mucosal delivery of biopharmaceuticals.
José das Neves is a Post-Doc researcher at INEB- Instituto de Engenharia Biomédica, University of Porto, Portugal. He obtained his PhD in Pharmaceutical Sciences from the University of Porto in 2013. His main research interests include vaginal drug delivery, nanotechnology-based drug carriers and biomaterials. His current research focuses specifically on the development of nanotechnology-based carrier systems for the vaginal and rectal delivery of antiretroviral drugs to be used in the development of anti-HIV microbicides.
Bruno Sarmento is an affiliated researcher at INEB – Instituto de Engenharia Biomédica, University of Porto, Portugal. He is also an assistant professor of pharmaceutical and biopharmaceutical technology at Instituto Superior de Ciências da Saúde-Norte, CESPU, Gandra, Portugal. He earned a Ph.D. in Pharmaceutical Technology at the University of Porto. He has extensive work in the development of nanocarriers for the oral delivery of biopharmaceuticals—namely insulin—and the establishment of novel in vitro intestinal permeability models. His current research focuses on nanomedicines and their applications in the pharmaceutical and biomedical fields.
MORE INFO: http://www.springer.com/