



@article {2512,
	title = {Albumin adsorption on alkanethiols self-assembled monolayers on gold electrodes studied by chronopotentiometry},
	journal = {BiomaterialsBiomaterials},
	volume = {24},
	year = {2003},
	note = {Cited By (since 1996): 31Export Date: 21 November 2012Source: ScopusCODEN: BIMADdoi: 10.1016/S0142-9612(03)00244-8PubMed ID: 12818541Language of Original Document: EnglishCorrespondence Address: Martins, M.C.L.; INEB - Inst. de Engenharia Biomed., Laborat{\'o}rio de Biomateriais, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal; email: cmartins@ibmc.up.ptChemicals/CAS: gold, 7440-57-5; thiol derivative, 13940-21-1; water, 7732-18-5; Albumins; Alkanes; Biocompatible Materials; Gold, 7440-57-5; Serum Albumin; Sulfhydryl CompoundsReferences: Ratner, B.D., Hoffman, A.S., Schoen, F.J., Lemons, J.L., (1996) Biomaterials science - an introduction to materials in medicine, , San Diego, CA, USA: Academic Press;Nakanishi, K., Sakiyama, T., Imamura, K., On the adsorption of proteins on solid surfaces, a common but very complicated phenomenon (2001) J Biosci Bioeng, 91, pp. 233-244; 
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},
	month = {2003///},
	pages = {3697 - 3706},
	abstract = {Chronopotentiometry was used to study the adsorption of human serum albumin (HSA) to self-assembled monolayers with the following terminal functional groups: CH                        3, COOH and OH. Surfaces were characterized by X-ray photoelectron spectroscopy, water contact angle measurements and cyclic voltammetry. HSA coverage of the different SAMs was investigated by chronopotentiometry and the total amount of adsorbed protein was determined using radiolabelled albumin. Both techniques have demonstrated that HSA adsorption to the different SAM-modified electrodes increases in the following order: OH\&lt;COOH\&lt;CH
                        3-terminated SAMs. A good correlation between coverage and total amount of HSA adsorbed was observed for long adsorption times (900s). {\textcopyright} 2003 Elsevier Science Ltd. All rights reserved.
},
	keywords = {Adsorption, Albumin, Albumin adsorption, Albumins, alkane, Alkanes, article, Biocompatible Materials, biomaterial, Biomaterials, carboxyl group, Chemical modification, Chronopotentiometry, Contact angle, correlation analysis, cyclic potentiometry, Cyclic voltammetry, electrochemistry, electrode, Electron Probe Microanalysis, Functional groups, gold, Humans, hydroxyl group, isotope labeling, methyl group, Monolayers, potentiometry, priority journal, protein analysis, Self assembly, Self-assembled monolayers, Serum Albumin, Sulfhydryl Compounds, Surface modification, Surface Properties, surface property, temperature, thiol derivative, Time Factors, Water, X ray photoelectron spectroscopy},
	isbn = {01429612 (ISSN)},
	url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-0038802804\&partnerID=40\&md5=d9b75bc199d3c909e08c53f4de329ce5},
	author = {Martins, M.C.L. and Fonseca, C. and Barbosa, M.A. and Ratner, B.D.}
}
