



@article {2627,
	title = {Granules of osteoapatite and glass-reinforced hydroxyapatite implanted in rabbit tibiae},
	journal = {Journal of Materials Science: Materials in MedicineJ. MATER. SCI. MATER. MED.},
	volume = {7},
	year = {1996},
	note = {Cited By (since 1996): 16Export Date: 21 November 2012Source: ScopusCODEN: JSMMELanguage of Original Document: EnglishCorrespondence Address: Afonso, A.; Faculty of Dental Medicine, University of Porto, Rua Dr Roberto Frias, 4200 Porto, PortugalChemicals/CAS: calcium phosphate, 10103-46-5, 13767-12-9, 14358-97-5, 7758-87-4; hydroxyapatite, 1306-06-5, 51198-94-8; magnesium, 7439-95-4; potassium, 7440-09-7; sodium, 7440-23-5References: Ravaglioli, A., Krajewski, A., (1992) Bioceramics-materials, Properties and Applications, p. 100. , Chapman \& Hall, London;Cranin, A.N., Ronen, E., Puntoff, R.S.H., Tobim, G., Dibeling, J.B., (1988) J. Biomed. Mater. Res., 22, p. 1165; 
De Groot, K., Klein, C.P.A.T., (1990) "Handbook of Bioactive Ceramics", Vol. II-Calcium Phosphate and Hydroxylapatite Ceramics, 2, p. 3. , edited by T. Yamamuro CRC Press, Boston; 
Hollinger, J.O., Schmitz, J.P., Mizgala, J.W., Hassler, C., (1989) J. Biomed. Mater. Res., 23, p. 17; 
Cavalheiro, J., Branco, R., Vasconcelos, M., (1991) Proceedings of the 4th International Conference on Bioceramics, p. 205. , edited by W. Bonfield, G. W. Hastings and K. E. Tanner, London, UK Butterworth-Heinemann, Oxford; 
Santos, J.D., Reis, R.L., Knowles, J.C., Monteiro, F.J., Hastings, G.W., (1994) Biomaterials, 15, p. 5; 
Nery, E.B., Legeros, R.Z., Lynch, K.L., Kalbleisch, J., (1988) J. Dent. Res., 67, p. 178; 
Ellinger, R.F., Nery, E.B., Lynch, K.L., (1986) Int. J. Period. Restor. Dent., 3, p. 223; 
Legeros, R.Z., Daculsi, G., (1990) "Handbook of Bioactive Ceramics", Vol. II-Calcium Phosphate and Hydroxylapatite Ceramics, 2, p. 17. , edited by T. Yamamuro CRC Press, Boston
},
	month = {1996///},
	pages = {507 - 510},
	abstract = {Granules of a modified hydroxyapatite, glass-reinforced hydroxyapatite composite and commercial hydroxyapatite were implanted in rabbit tibiae. Histological studies were carried out after 1 and 2 months implantation periods using light and fluorescence microscopy. A much higher percentage of bone contact was developed for both the glass-reinforced hydroxyapatite composite and the modified hydroxyapatite when compared to commercial hydroxyapatite (89-91\% versus 66\%) after 2 months implantation. The mechanism of bone formation and growth around implants is discussed in terms of the influence of elements incorporated into these novel materials which are commonly found in bone tissues, such as Na, K and Mg, and the presence of a soluble β-tricalcium phosphate phase in the microstructure of the composite.},
	keywords = {animal experiment, animal tissue, article, Bone, Bone formation, bone growth, Calcium Compounds, calcium phosphate, Composite materials, Fiber reinforced materials, glass, Glass fibers, Glass reinforced hydroxyapatite, Granular materials, histology, hydroxyapatite, implant, Implants (surgical), Magnesium, Microstructure, Modified hydroxyapatite, nonhuman, Optical microscopy, ossification, Osteoapatite, Oxides, Phosphates, Physiological models, potassium, priority journal, rabbit, Rabbit tibiae, Sodium, tibia, X ray diffraction analysis},
	isbn = {09574530 (ISSN)},
	url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-0029666749\&partnerID=40\&md5=48a404008151489ff92ea9bc191cf374},
	author = {Afonso, A. and Santos, J.D. and Vasconcelos, M. and Branco, R. and Cavalheiro, J.}
}
